RESOURCES

1. The MONEAD study
https://web.emmes.com/study/monead/
This site is the original NEAD Study background information and the update to the study. Since the first publications in 2007-08, the MONEAD Study continued with more research objectives and concludes in 2017. See contact information for university medical center participants.

2. NIH
https://clinicaltrials.gov/ct2/show/results/NCT01730170
The National Institute of Health listing for the MONEAD Study, 1999-current.

3. Mothers Collect Data
https://itunes.apple.com/us/app/id586523051
The app MONEAD participants in use to input new research data to continue studying the effects of antiepileptic drugs.

4. PubMed
http://www.ncbi.nlm.nih.gov/pubmed/23352199
PubMed entry of Lancet Neurology article, Fetal Antiepileptic Drug Exposure and cognitive Outcomes at Age 6 Years (NEAD Study): a prospective observational study, March 2013.

5. Letter to the Editor and NEAD Study Response
http://www.nejm.org/doi/full/10.1056/NEJMoa0803531
The New England Journal of Medicine article, Cognitive Function of 3 Years of Age After Fetal Exposure to Antiepileptic Drugs. April 2009, with an abstract, original article, references, citing articles, letters (responding to the article), and response from the authors.

6. 2015 Journal Update on NEAD Study
http://www.neurology.org/content/84/14_Supplement/S6.002
Neurology, Re-analyses of Outcomes of Fetal Valproate Exposure in the NEAD Study (S6.002), online version April 8, 2015. Abstract.

7. Complete Article from Lancet Neurology 2013
https://www.researchgate.net/publication/235374322_Fetal_antiepileptic_drug_exposure_and_cognitive_outcomes_at_age_6_years_NEAD_stud
Shows pages 1-9 of the Lancet Neurology article, Fetal Antiepileptic Drug Exposure and Cognitive Outcomes at 6 years of Age: a prospective observational study, January 2016.

8. FDA
http://www.fda.gov/Drugs/DrugSafety/ucm350684.htm
FDA U. S. Food and Drug Administration, FDA Drug Safety Communication: Valproate Anti-seizure Products Contra-indicated for Migraine Prevention in Pregnant Women due to Decreased IQ Scores in Exposed Children, May6, 2013.
Includes:
Safety Announcement
Facts About Valproate
Additional Information for Patients
Additional Information for Healthcare Professionals
Data Summary
References
Available to print in both English and Spanish.

9. Quick Access to Several Journal Reviews
http://www.pubpdf.com/pub/19369666/Cognitive-function-at-3-years-of-age-after-fetal-exposure-to-antiepileptic-drugs
Just want to get an idea of the journal articles without spending too much time? This is a quick access to several of the articles referenced here.

10. Review on NEAD Study Breastfeeding Recommendations
http://www.epilepsycurrents.org/doi/pdf/10.5698/1535-7597-15.1.10
Article in Epilepsy Currents by Elizabeth Powell, PhD, Breast is Still Best: No Harmful Effects of Breastfeeding in Women Taking Antiepileptic Drugs, January/February 2015.

11. Journal Review and Critique Including More Uses for Depakote
http://ahrp.org/nejm-study-confirms-exposure-to-depakote-lowers-childrens-iq/
This is a brief explanation of the New England Journal of Medicine published with commentary and critique.
“Fewer than half of all anti-epileptic drug prescriptions are written for epilepsy or seizures- the majority of prescriptions are intended for pain management and psychiatric indications.”

12. Brief Review of the NEAD Study
https://womensmentalhealth.org/posts/outcomes-of-children-exposed-to-anti-epileptic-drugs-in-pregnancy-no-good-news-for-valproate/
Massachusetts General Hospital Center for Women’s Mental Health website explains the NEAD Study results and gives a recommendation to those women using them.
Obviously, the quote in Resource # 12 is factual. Why else would it be included on the MGH Center for Women’s Mental Health website?

13. Journal Review Includes the Birth Defects from Depakote
http://fightforvictims.com/depakote-side-effects-depakote-use-during-pregnancy-can-lower-childrens-iqs-confirms-nead-study/3250
This web article clearly states the type of birth defects that can occur from Depakote (valproate) and lists them before explaining the NEAD Study results and giving his commentary.

14. British Journal Review on NEAD Study
http://brain.oxfordjournals.org/content/brain/134/2/396.full.pdf
Includes the Tables 1,2,3, 4, and 5 of the original article results from 2004. This is from Brain a Journal of Neurology, 2011.

15. Research in Europe
http://archneur.jamanetwork.com/article.aspx?articleid=1741977
Study from Norway in JAMA Neurology, 2013, that also follows pregnant women with epilepsy to determine the effects of epileptic drugs on the fetus.