1. The MONEAD study
This site is the original NEAD Study background information and the update to the study. Since the first publications in 2007-08, the MONEAD Study continued with more research objectives and concludes in 2017. See contact information for university medical center participants.
The National Institute of Health listing for the MONEAD Study, 1999-current.
3. Mothers Collect Data
The app MONEAD participants in use to input new research data to continue studying the effects of antiepileptic drugs.
PubMed entry of Lancet Neurology article, Fetal Antiepileptic Drug Exposure and cognitive Outcomes at Age 6 Years (NEAD Study): a prospective observational study, March 2013.
5. Letter to the Editor and NEAD Study Response
The New England Journal of Medicine article, Cognitive Function of 3 Years of Age After Fetal Exposure to Antiepileptic Drugs. April 2009, with an abstract, original article, references, citing articles, letters (responding to the article), and response from the authors.
6. 2015 Journal Update on NEAD Study
Neurology, Re-analyses of Outcomes of Fetal Valproate Exposure in the NEAD Study (S6.002), online version April 8, 2015. Abstract.
7. Complete Article from Lancet Neurology 2013
Shows pages 1-9 of the Lancet Neurology article, Fetal Antiepileptic Drug Exposure and Cognitive Outcomes at 6 years of Age: a prospective observational study, January 2016.
FDA U. S. Food and Drug Administration, FDA Drug Safety Communication: Valproate Anti-seizure Products Contra-indicated for Migraine Prevention in Pregnant Women due to Decreased IQ Scores in Exposed Children, May6, 2013.
Facts About Valproate
Additional Information for Patients
Additional Information for Healthcare Professionals
Available to print in both English and Spanish.
9. Quick Access to Several Journal Reviews
Just want to get an idea of the journal articles without spending too much time? This is a quick access to several of the articles referenced here.
10. Review on NEAD Study Breastfeeding Recommendations
Article in Epilepsy Currents by Elizabeth Powell, PhD, Breast is Still Best: No Harmful Effects of Breastfeeding in Women Taking Antiepileptic Drugs, January/February 2015.
11. Journal Review and Critique Including More Uses for Depakote
This is a brief explanation of the New England Journal of Medicine published with commentary and critique.
“Fewer than half of all anti-epileptic drug prescriptions are written for epilepsy or seizures- the majority of prescriptions are intended for pain management and psychiatric indications.”
12. Brief Review of the NEAD Study
Massachusetts General Hospital Center for Women’s Mental Health website explains the NEAD Study results and gives a recommendation to those women using them.
Obviously, the quote in Resource # 12 is factual. Why else would it be included on the MGH Center for Women’s Mental Health website?
13. Journal Review Includes the Birth Defects from Depakote
This web article clearly states the type of birth defects that can occur from Depakote (valproate) and lists them before explaining the NEAD Study results and giving his commentary.
14. British Journal Review on NEAD Study
Includes the Tables 1,2,3, 4, and 5 of the original article results from 2004. This is from Brain a Journal of Neurology, 2011.
15. Research in Europe
Study from Norway in JAMA Neurology, 2013, that also follows pregnant women with epilepsy to determine the effects of epileptic drugs on the fetus.